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Article

Gastrointestinal stromal tumor and its targeted therapeutics.

Chinese journal of cancer - 1 May 2011

Dupart Jheri, Zhang Wei, Trent Jonathan C

Abstract excerpt

Over the past 60 years, investigators of basic science, pathology, and clinical medicine have studied gastrointestinal stromal tumor (GIST) and made minor advances in patient care. Recent discoveries have led to an understanding of the biological role of KIT and platelet-derived growth factor receptor-α in GIST and the development of the tyrosine kinase inhibitor imatinib mesylate (Gleevec, formerly STI-571), one...

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Source

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Identifiers

PMID: 21527063
DOI: 10.5732/cjc.011.10062
PMCID: PMC4013395

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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