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Article

Alterations of the c-kit gene in testicular germ cell tumors.

Cancer science - 1 Jun 2003

Sakuma Yuji, Sakurai Shinji, Oguni Sachiko, Hironaka Mitsugu, Saito Ken

Abstract excerpt

Expression and gain-of-function mutation of the c-kit gene, that encodes a receptor tyrosine kinase (KIT), have been reported in mast cell tumors and gastrointestinal stromal tumors (GISTs). Among human testicular germ cell tumors (GCTs), seminomas and seminoma components of mixed GCTs have also...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12824871
DOI: 10.1111/j.1349-7006.2003.tb01470.x
PMCID: PMC11160296

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12824871-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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