Article
GEIRA: gene-environment and gene-gene interaction research application.
European journal of epidemiology - 1 Jul 2011
Ding Bo, Källberg Henrik, Klareskog Lars, Padyukov Leonid, Alfredsson Lars
Abstract excerpt
The GEIRA (Gene-Environment and Gene-Gene Interaction Research Application) algorithm and subsequent program is dedicated to genome-wide gene-environment and gene-gene interaction analysis. It implements concepts of both additive and multiplicative interaction as well as calculations based on dominant, recessive and co-dominant genetic models, respectively. Estimates of interactions are incorporated in a single...
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