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Article

Gene-environment interactions and their impact on human health.

Genes and immunity - 1 Feb 2023

Virolainen Samuel J, VonHandorf Andrew, Viel Kenyatta C M F, Weirauch Matthew T, Kottyan Leah C

Abstract excerpt

The molecular processes underlying human health and disease are highly complex. Often, genetic and environmental factors contribute to a given disease or phenotype in a non-additive manner, yielding a gene-environment (G × E) interaction. In this work, we broadly review current knowledge on the impact of gene-environment interactions on human health. We first explain the independent impact of genetic variation...

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Identifiers

PMID: 36585519
DOI: 10.1038/s41435-022-00192-6
PMCID: PMC9801363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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