Article
SWI/SNF complexes containing Brahma or Brahma-related gene 1 play distinct roles in smooth muscle development.
Molecular and cellular biology - 1 Jul 2011
Zhang Min, Chen Meng, Kim Ju-Ryoung, Zhou Jiliang, Jones Rebekah E, Tune Johnathan D, Kassab Ghassan S, Metzger Daniel, Ahlfeld Shawn, Conway Simon J, Herring B Paul
Abstract excerpt
SWI/SNF ATP-dependent chromatin-remodeling complexes containing either Brahma-related gene 1 (Brg1) or Brahma (Brm) play important roles in mammalian development. In this study we examined the roles of Brg1 and Brm in smooth muscle development, in vivo, through generation and analysis of mice harboring a smooth muscle-specific knockout of Brg1 on wild-type and Brm null backgrounds. Knockout of Brg1 from smooth...
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