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Article

Promoter Identification and Transcription Analysis of Penicillin-Binding Protein Genes in Streptococcus pneumoniae R6.

Microbial drug resistance (Larchmont, N.Y.) - 1 Sept 2016

Peters Katharina, Pipo Julia, Schweizer Inga, Hakenbeck Regine, Denapaite Dalia

Abstract excerpt

Penicillin-binding proteins (PBPs) are membrane-associated enzymes, which are involved in the last two steps of peptidoglycan biosynthesis, and some of them are key players in cell division. Furthermore, they are targets of β-lactams, the most widely used antibiotics. Nevertheless, very little is known about the expression and regulation of PBP genes. Using transcriptional mapping, we now determined the promoter...

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Identifiers

PMID: 27409661
DOI: 10.1089/mdr.2016.0084
PMCID: PMC5036317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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