Article
The Drosophila gene disruption project: progress using transposons with distinctive site specificities.
Genetics - 1 Jul 2011
Bellen Hugo J, Levis Robert W, He Yuchun, Carlson Joseph W, Evans-Holm Martha, Bae Eunkyung, Kim Jaeseob, Metaxakis Athanasios, Savakis Charalambos, Schulze Karen L, Hoskins Roger A, Spradling Allan C
Abstract excerpt
The Drosophila Gene Disruption Project (GDP) has created a public collection of mutant strains containing single transposon insertions associated with different genes. These strains often disrupt gene function directly, allow production of new alleles, and have many other applications for analyzing gene function. Here we describe the addition of ∼7600 new strains, which were selected from >140,000 additional P or...
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