Article
IL-23 receptor regulation by Let-7f in human CD4+ memory T cells.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 2011
Li Zhaoxia, Wu Feng, Brant Steven R, Kwon John H
Abstract excerpt
CD4(+) memory T cells include the Th17 cell population, which has been shown to be implicated in autoimmune and inflammatory diseases. These memory T cells express higher IL-23R and produce more IL-17 compared with their naive counterparts. However, the molecular mechanisms that regulate IL-23R expression in human T cells are not completely understood. MicroRNAs play important roles in a wide range of biological...
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