Article
The Impact of MicroRNA-223-3p on IL-17 Receptor D Expression in Synovial Cells
5 Jan 2017
Abstract excerpt
OBJECTIVE: Rheumatoid arthritis (RA) is an autoimmune inflammatory disease affecting joints. Elevated plasma levels of microRNA-223-3p (miR-223-3p) in patients with RA are implicated in the pathogenesis of the disease. This study aimed to analyze the functional role of miR-223-3p in the pathogenesis of RA by overexpressing miR-223-3p in synovial cell lines. METHODS: Arthritis was induced in the RA model of SKG...
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