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Article

TET2 mutations in secondary acute myeloid leukemias: a French retrospective study.

Haematologica - 1 Jul 2011

Kosmider Olivier, Delabesse Eric, de Mas Véronique Mansat, Cornillet-Lefebvre Pascale, Blanchet Odile, Delmer Alain, Recher Christian, Raynaud Sophie, Bouscary Didier, Viguié Franck, Lacombe Catherine, Bernard Olivier A, Ifrah Norbert, Dreyfus François, Fontenay Michaëla

Abstract excerpt

Ten-eleven translocation 2 (TET2) mutations have been involved in myeloid malignancies. This retrospective study aims at evaluating the frequency and impact of TET2 mutations in 247 secondary acute myeloid leukemia cases referred to as myelodysplasia-related changes (n=201) or therapy-related (n=46) leukemias. Mutation of at least one copy of the TET2 gene was detected in 49 of 247 (19.8%) patients who presented...

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Source

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Identifiers

PMID: 21508122
DOI: 10.3324/haematol.2011.040840
PMCID: PMC3128227

Genes

TET2
FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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