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Article

Ionotropic glutamate receptor gene GRIK3 SER310ALA functional polymorphism is related to delirium tremens in alcoholics.

The pharmacogenomics journal - 1 Jan 2000

Preuss U W, Zill P, Koller G, Bondy B, Hesselbrock V, Soyka M

Abstract excerpt

Upregulation of glutamatergic neurotransmission resulting from chronic ethanol intoxication may cause a hyperexcitable state during alcohol withdrawal, which may lead to seizures and delirium tremens. The aim of our study was to evaluate the association between a history of alcohol withdrawal-induced seizures and delirium tremens, and a functional polymorphism (Ser310Ala) of the GRIK3 gene coding for the...

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Source

Identifiers

PMID: 16314883
DOI: 10.1038/sj.tpj.6500343

Genes

GRIK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Ionotropic glutamate receptor gene GRIK3 SER310ALA functional polymorphism is related to delirium tremens in alcoholics.PMID 16314883Read ↗

Family-based and case-control association studies of glutamate receptor GRIK3 Ser310Ala polymorphism in Polish patients and families with alcohol dependence.Semantic proximity Read ↗

Family-based and case-control study of glutamate receptor GRIK3 Ser310Ala polymorphism in alcohol dependence.Semantic proximity Read ↗

Association between the ionotropic glutamate receptor kainate 3 (GRIK3) ser310ala polymorphism and schizophrenia.Semantic proximity Read ↗

Association between the ionotropic glutamate receptor kainate3 (GRIK3) Ser310Ala polymorphism and schizophrenia in the Indian population.Semantic proximity Read ↗

GRIN1 locus may modify the susceptibility to seizures during alcohol withdrawal.Semantic proximity Read ↗

Association of markers in the 3' region of the GluR5 kainate receptor subunit gene to alcohol dependence.Semantic proximity Read ↗

No association between the ionotropic glutamate receptor kainate 3 gene ser310ala polymorphism and schizophrenia.Semantic proximity Read ↗

An association of GRIK3 Ser310Ala functional polymorphism with personality traits.Semantic proximity Read ↗

Association between a polymorphism in the promoter of a glutamate receptor subunit gene (GRIN2A) and alcoholism.Semantic proximity Read ↗

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Polymorphisms in the NMDA subunit 2B are not associated with alcohol dependence and alcohol withdrawal-induced seizures and delirium tremens.Semantic proximity Read ↗

The genetics of deliria.Semantic proximity Read ↗

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