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Article

Family-based and case-control association studies of glutamate receptor GRIK3 Ser310Ala polymorphism in Polish patients and families with alcohol dependence.

Neuroscience letters - 27 Mar 2006

Samochowiec Jerzy, Grzywacz Anna, Kucharska-Mazur Jolanta, Samochowiec Agnieszka, Horodnicki Jan, Pelka-Wysiecka Justyna, Syrek Szymon

Abstract excerpt

The aim of this study was to evaluate the role of the GRIK3 functional polymorphism (Ser310Ala) in the pathogenesis of alcoholism. This polymorphism was investigated in two types of studies: (1) the association study in a whole group of alcoholics (116 patients fulfilling ICD-10 alcohol dependence (AD) criteria and 255 controls, Polish descent) and homogenous overlapping subgroups of patients with: a history of...

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Alcoholism
Family
Heterozygote
Incidence
Poland

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Subunits

Receptors, Kainic Acid

Risk Assessment

Source

Identifiers

PMID: 16356644
DOI: 10.1016/j.neulet.2005.11.030

Genes

GRIK3

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