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Article

Proteolytic cleavage of Notch: "HIT and RUN".

Current molecular medicine - 1 Jun 2011

van Tetering G, Vooijs M

Abstract excerpt

The Notch pathway is a highly conserved signaling pathway in multicellular eukaryotes essential in controlling spatial patterning, morphogenesis and homeostasis in embryonic and adult tissues. Notch proteins coordinate cell-cell communication through receptor-ligand interactions between adjacent cells. Notch signaling is frequently deregulated by oncogenic mutation or overexpression in many cancer types. Notch...

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Identifiers

PMID: 21506924
DOI: 10.2174/156652411795677972
PMCID: PMC4050734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Proteolytic cleavage of Notch: "HIT and RUN".PMID 21506924Read ↗

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