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Article

Platelet receptor gain-of-function single nucleotide polymorphisms in carotid and vertebral stenosis patients.

Journal of thrombosis and thrombolysis - 1 Aug 2011

Lugli Andrea Kopp, Brown Martin M, Steffel Jan, Büchi Linda, Förnzler Dorothee, Dupont Annabelle, Gaussem Pascale, Forestier Marc, Beer Juerg H

Abstract excerpt

The role of platelet receptor gain-of-function single nucleotide polymorphisms (SNP) in cardiovascular disease is controversial. We hypothesised that certain SNPs may accelerate the development of carotid artery stenosis. The intronic PAR-1 receptor intervening sequence-14 A/T (IVSn-14 A/T) polymorphism and three additional platelet receptor polymorphisms, i.e. GPIa (807C/T), GPIbα (5T/C) and HPA-1a/HPA-1b (Pl...

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PMID: 21505785
DOI: 10.1007/s11239-011-0586-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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