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Article

The 2 Gene Coding Sequence T807/A873 of the Platelet Collagen Receptor Integrin 2β1 Might Be a Genetic Risk Factor for the Development of Stroke in Younger Patients

1 Jun 1999

Abstract excerpt

The polymorphisms C807T and G873A of the platelet integrin alpha2beta1 (collagen receptor glycoprotein [GP] Ia-IIa) are linked to the expression density of this receptor. The GPIa T807/A873 allele causes a higher receptor expression, enhancing platelet binding to collagen. This might present a genetic predisposition for the development of thromboembolic complications. In this case-control study, the genotypes of...

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PMID: 10339462
DOI: 10.1182/blood.v93.11.3583

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Related research

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The 2 Gene Coding Sequence T807/A873 of the Platelet Collagen Receptor Integrin 2β1 Might Be a Genetic Risk Factor for the Development of Stroke in Younger PatientsPMID 10339462Read ↗

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The Influence of Platelet Collagen Receptor Polymorphisms in Hemostasis and Thrombotic DiseaseSemantic proximity Read ↗

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