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Article

Genetics of platelet receptor single-nucleotide polymorphisms: clinical implications in thrombosis.

Annals of medicine - 1 Dec 2000

Beer J H, Pederiva S, Pontiggia L

Abstract excerpt

Several single-nucleotide polymorphisms (SNPs) of platelet receptors have been implicated to be associated with an increased risk of arterial thrombosis; this review focuses on the mechanisms and the clinical significance of two specific single-nucleotide polymorphisms, ie the GP IIIa L33P (=PlA1/2) and the GP Ia 807 C/T. Whereas the mechanism of P1A2 is thought to result from 'gain of receptor function' (and...

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PMID: 11209974

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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