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Article

Prolactin and prolactin receptor gene polymorphisms in multiple sclerosis and systemic lupus erythematosus.

Human immunology - 1 Feb 2003

Mellai Marta, Giordano Mara, D'Alfonso Sandra, Marchini Maurizio, Scorza Raffaella, Danieli M, Leone Maurizio, Ferro Isabella, Liguori Maria, Trojano Maria, Ballerini Clara, Massacesi Luca, Cannoni Stefania, Bomprezzi Roberto, Momigliano-Richiardi Patricia

Abstract excerpt

Genes encoding for prolactin (PRL) and its receptor (PRLR) are possible candidates for multiple sclerosis (MS) and systemic lupus erythematosus (SLE) susceptibility. In fact: (1) a prolactin secretion dysfunction has been described in several autoimmune diseases including SLE and MS and their animal models; (2) both PRL and PRLR are structurally related to members of the cytokine/hematopoietin family and have a...

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Source

Identifiers

PMID: 12559630
DOI: 10.1016/s0198-8859(02)00804-2

Genes

PRL
PRLR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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