Article
4G/5G plasminogen activator inhibitor-1 and -308 A/G tumor necrosis factor-α promoter gene polymorphisms in Argentinean lupus patients: focus on lupus nephritis.
Clinical and experimental medicine - 1 Feb 2014
Muñoz Sebastián Andrés, Aranda Federico, Allievi Alberto, Orden Alberto Omar, Perés Wingeyer Silvia, Trobo Rosana, Alvarez Analía, Eimon Alicia, Barreira Juan Carlos, Schneeberger Emilce, Dal Pra Fernando, Sarano Judith, Hofman Julio, Chamorro Julián, de Larrañaga Gabriela
Abstract excerpt
We investigated the relationship between the 4G/5G plasminogen activator inhibitor (PAI-1) and -308 A/G tumor necrosis factor-α (TNF-α) polymorphisms and the clinical and biochemical features of systemic lupus erythematosus (SLE) in an Argentinean patient cohort. A total of 402 patients were studied, including 179 SLE patients and 223 healthy individuals. PCR-RLFP was used to determine the genotypes of the 4G/5G...
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