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Article

Trisomy 21 in neoplastic cells

6 Jun 2005

Abstract excerpt

Trisomy 21 as an acquired clonal chromosome change has been described in 642 of the 10,625 human neoplasms with chromosome aberrations known from the cytogenetic literature. A total of 590 of the 642 cases (92%) are hematologic disorders and malignant lymphomas. The incidence of trisomy 21 is similar (4.1%-6.7%) in acute myeloid leukemia (AML), chronic myeloid leukemia, myeloproliferative disorders,...

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Identifiers

PMID: 2149959
DOI: 10.1002/ajmg.1320370752

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