Article
DiGIR1 and NaGIR1: naturally occurring group I-like ribozymes with unique core organization and evolved biological role.
Biochimie - 1 Sept 2002
Johansen Steinar, Einvik Christer, Nielsen Henrik
Abstract excerpt
The group I-like ribozyme GIR1 is a unique example of a naturally occurring ribozyme with an evolved biological function. GIR1 generates the 5'-end of a nucleolar encoded messenger RNA involved in intron mobility. GIR1 is found as a cis-cleaving ribozyme within two very different rDNA group I introns (twin-ribozyme introns) in distantly related organisms. The Didymium GIR1 (DiGIR1) and Naegleria GIR1 (NaGIR1)...
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