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Article

Phenotypic changes in calbindin D28K immunoreactivity in the hippocampus of Fmr1 knockout mice.

The Journal of comparative neurology - 1 Sept 2011

Real M Angeles, Simón M Pilar, Heredia Raúl, de Diego Yolanda, Guirado Salvador

Abstract excerpt

Fragile X syndrome (FXS), the most prevalent form of inherited mental retardation, is caused by the lack of FMRP (fragile mental retardation protein) as a result of the transcriptional silencing of the FMR1 gene. Here we analyze the immunohistochemical expression of the calbindin D28K protein in the hippocampus of Fmr1 knockout (KO) mice and compare it with that of their wildtype (WT) littermates. The spatial...

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Source

Identifiers

PMID: 21491426
DOI: 10.1002/cne.22643

Genes

FMR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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