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Article

The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans.

Development (Cambridge, England) - 1 May 2011

Neukomm Lukas Jakob, Nicot Anne-Sophie, Kinchen Jason Michael, Almendinger Johann, Pinto Sérgio Morgado, Zeng Sheng, Doukoumetzidis Kimon, Tronchère Hélène, Payrastre Bernard, Laporte Jocelyn Franck, Hengartner Michael Otmar

Abstract excerpt

Multicellular organisms use programmed cell death to eliminate unwanted or potentially harmful cells. Improper cell corpse removal can lead to autoimmune diseases. The development of interventional therapies that increase engulfment activity could represent an attractive approach to treat such diseases. Here, we describe mtm-1, the Caenorhabditis elegans homolog of human myotubularin 1, as a potential negative...

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PMID: 21490059
DOI: 10.1242/dev.060012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans.PMID 21490059Read ↗

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