Article
A polymorphism in ACE2 is associated with a lower risk for fatal cardiovascular events in females: the MORGAM project.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2011
Vangjeli Ciara, Dicker Patrick, Tregouet David-Alexandre, Shields Denis C, Evans Alun, Stanton Alice V
Abstract excerpt
Angiotensin II, a vasoconstrictor and the main effector molecule of the renin-angiotensin system, is known to influence inflammation, thrombosis, low-density lipoprotein oxidation and growth factors, all of which contribute to cardiovascular disease. The associations of polymorphisms in the angiotensin-converting enzyme 2 (ACE2) gene with cardiovascular risk have not been fully determined. Single nucleotide...
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