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Article

BRCA2 variants and cardiovascular disease in a multi-ethnic study.

BMC medical genetics - 18 Jul 2012

Zbuk Kevin, Xie Changchun, Young Robin, Heydarpour Mahyar, Pare Guillaume, Davis A Darlene, Miller Ruby, Lanktree Matthew B, Saleheen Danish, Danesh John, Yusuf Salim, Engert James C, Hegele Robert A, Anand Sonia S

Abstract excerpt

BACKGROUND: Germline mutations of BRCA1/2 are associated with hereditary breast and ovarian cancer. Recent data suggests excess mortality in mutation carriers beyond that conferred by neoplasia, and recent in vivo and in vitro studies suggest a modulatory role for BRCA proteins in endothelial and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22809218
DOI: 10.1186/1471-2350-13-56
PMCID: PMC3464815

Genes

BRCA2
BRCA1
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22809218-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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