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Article

Fibroblast growth factor 23 overexpression impacts negatively on dentin mineralization and dentinogenesis in mice.

Clinical and experimental pharmacology & physiology - 1 Jun 2011

Chen Ling, Liu Hong, Sun Wen, Bai Xiuying, Karaplis Andrew C, Goltzman David, Miao Dengshun

Abstract excerpt

1. Though previous studies have shown that fibroblast growth factor 23 (FGF23) mRNA expression localizes in ameloblasts and odontoblasts in teeth, it is unclear what effect FGF23 overexpression has on dentin mineralization and dentinogenesis. Toward this end, the phenotypes of mandibles and teeth were compared between 6-week-old FGF23 transgenic mice and their wild-type littermates by radiography, microcomputed...

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Source

Identifiers

PMID: 21488937
DOI: 10.1111/j.1440-1681.2011.05526.x

Genes

FGF23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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