Article
FOXD3 regulates migration properties and Rnd3 expression in melanoma cells.
Molecular cancer research : MCR - 1 May 2011
Katiyar Pragati, Aplin Andrew E
Abstract excerpt
Forkhead transcription factor, Foxd3, plays a critical role during development by controlling the lineage specification of neural crest cells. Notably, Foxd3 is highly expressed during the wave of neural crest cell migration that forms peripheral neurons and glial cells but is downregulated prior to migration of cells that give rise to the melanocytic lineage. Melanoma is the deadliest form of skin cancer and is...
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