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Article

A fully integrated and automated detection system for single nucleotide polymorphisms of UGT1A1 and CYP2C19.

Oncology research - 1 Jan 2011

Ureshino Norio, Aragane Naoko, Nakamura Tomomi, Ide Masaru, Mochinaga Sakiko, Fukushima Noriyasu, Hayashi Shinichiro, Sueoka Eizaburo, Kimura Shinya

Abstract excerpt

The need for examinations of single nucleotide polymorphisms (SNPs) on drug metabolizing enzymes is accelerating. Especially, SNPs of UTG1A1 and CYP2C19 are important for patients who are treated with irinotecan and proton pump inhibitors, respectively. Thus, a method for the rapid, fully automated, and accurate measurement of these SNPs is desired. We genotyped 109 Japanese volunteers for UGT1A1*6, UGT1A1*28,...

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Identifiers

PMID: 21473286
DOI: 10.3727/096504011x12935427587687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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