Article
An automated rapid detection system using the quenching probe method for detecting interleukin 28B and inosine triphosphatase single nucleotide polymorphisms in chronic hepatitis C.
Journal of viral hepatitis - 1 Apr 2013
Takahashi H, Mizuta T, Oeda S, Isoda H, Nakashita S, Kawaguchi Y, Izumi N, Hirai M, Kurose K, Iwane S, Eguchi Y, Kimura S, Anzai K, Ozaki I
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in the interleukin 28B gene (IL28B) are good pretreatment predictors of anti-hepatitis C virus (HCV) therapy with interferon. SNPs of the inosine triphosphatase (ITPA) gene are associated with reduced haemoglobin levels during treatment with ribavirin. The i-densy™ (Arkray, Inc.), which is based on the quenching probe (QP) method, automatically detects target genes in blood...
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