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Article

Rapid and sensitive detection of UGT1A1 polymorphisms associated with irinotecan toxicity by a novel DNA microarray.

Cancer science - 1 Jul 2017

Tsunedomi Ryouichi, Hazama Shoichi, Okayama Naoko, Oka Masaaki, Nagano Hiroaki

Abstract excerpt

Recent developments in the field of human genomics have greatly enhanced the potential for precision and personalized medicine. We have developed a novel DNA microarray, using a 3-mm square chip coated with diamond-like carbon to enhance the signal-to-background ratio, for use as an in vitro diagnostic tool in precision medicine. To verify the genotyping effectiveness of this newly developed DNA microarray we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28474802
DOI: 10.1111/cas.13272
PMCID: PMC5497725

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