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Article

Zebrafish pax5 regulates development of the utricular macula and vestibular function.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2006

Kwak Su-Jin, Vemaraju Shruti, Moorman Stephen J, Zeddies David, Popper Arthur N, Riley Bruce B

Abstract excerpt

The zebrafish otic vesicle initially forms with only two sensory epithelia, the utricular and saccular maculae, which primarily mediate vestibular and auditory function, respectively. Here, we test the role of pax5, which is preferentially expressed in the utricular macula. Morpholino knockdown of pax5 disrupts vestibular function but not hearing. Neurons of the statoacoustic ganglion (SAG) develop normally....

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PMID: 17013878
DOI: 10.1002/dvdy.20961

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SAG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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