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Article

β2-Adrenergic ion-channel coupled receptors as conformational motion detectors.

PloS one - 25 Mar 2011

Caro Lydia N, Moreau Christophe J, Revilloud Jean, Vivaudou Michel

Abstract excerpt

Ion Channel-Coupled Receptors (ICCRs) are artificial proteins comprised of a G protein-coupled receptor and a fused ion channel, engineered to couple channel gating to ligand binding. These novel biological objects have potential use in drug screening and functional characterization, in addition to providing new tools in the synthetic biology repertoire as synthetic K(+)-selective ligand-gated channels. The ICCR...

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Identifiers

PMID: 21464970
DOI: 10.1371/journal.pone.0018226
PMCID: PMC3064670

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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