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Article

Characterization of Chinese hamster ovary cells with impaired spreading properties on fibronectin.

Journal of cell science - 1 Jul 1990

Joseph L B, Kreutzer D L, Tanzer M L

Abstract excerpt

The development of receptor-defective or -deficient mutants can be applied to the investigation of cell-matrix interactions including cell adherence and spreading. In the present study we developed a series of ethyl methyl sulfonate (EMS)-induced Chinese hamster ovary (CHO) cell mutants, which adhere to fibronectin but have impaired spreading characteristics. Using morphometric analysis, a significant suppression...

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PMID: 2146277
DOI: 10.1242/jcs.96.3.519

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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