Article
A preliminary study on the association of single nucleotide polymorphisms of interleukin 4 (IL4), IL13, IL4 receptor alpha (IL4Rα) & Toll-like receptor 4 (TLR4) genes with asthma in Indian adults.
The Indian journal of medical research - 1 Dec 2015
Davoodi Parisa, Mahesh P A, Holla Amrutha D, Ramachandra Nallur B
Abstract excerpt
BACKGROUND & OBJECTIVES: Interleukin 4 (IL4) and IL13 genes are believed to be responsible for inflammation of the airways in asthmatics. These share a common receptor component called IL4Rα which is another potentially important candidate gene linked to asthma phenotypes. Another gene Toll-like receptor 4 (TLR4) might affect the incidence or progression of asthma through the expression of proinflammatory genes....
Topics
- Adult
- Asthma
- Female
- Humans
- India
- Interleukin-13
- Interleukin-4
- Interleukin-4 Receptor alpha Subunit
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Toll-Like Receptor 4
- Young Adult