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Article

Emergence of minor drug-resistant HIV-1 variants after triple antiretroviral prophylaxis for prevention of vertical HIV-1 transmission.

PloS one - 1 Jan 2012

Hauser Andrea, Sewangi Julius, Mbezi Paulina, Dugange Festo, Lau Inga, Ziske Judith, Theuring Stefanie, Kuecherer Claudia, Harms Gundel, Kunz Andrea

Abstract excerpt

BACKGROUND: WHO-guidelines for prevention of mother-to-child transmission of HIV-1 in resource-limited settings recommend complex maternal antiretroviral prophylaxis comprising antenatal zidovudine (AZT), nevirapine single-dose (NVP-SD) at labor onset and AZT/lamivudine (3TC) during labor and one week postpartum. Data on resistance development selected by this regimen is not available. We therefore analyzed the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22384138
DOI: 10.1371/journal.pone.0032055
PMCID: PMC3285650

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