Article
Analysis of matrix metalloproteinase-9 gene polymorphism -1562 C/T in patients suffering from systemic sclerosis with and without ulcers.
International journal of molecular medicine - 1 Jun 2011
Skarmoutsou Evangelia, D'Amico Fabio, Marchini Maurizio, Stivala Franca, Malaponte Grazia, Scorza Raffaella, Mazzarino Maria Clorinda
Abstract excerpt
The objective of this study was to determine whether the matrix metalloproteinase-9 (MMP-9) rs3918242 single nucleotide polymorphism may confer susceptibility to systemic sclerosis (SSc) with and without ulcers in an Italian Caucasian population. The MMP-9 rs3918242 functional polymorphism was genotyped in 461 subjects of Italian Caucasian origin: 228 patients with SSc (92 with and 136 without ulcers) and 233...
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