Article
Characterization of an Escherichia coli mutant pleiotropically altered in membrane-bound oxidoreductase activities.
Microbiology and immunology - 1 Jan 1990
Cox J C, Goldschmidt E P, Jurtshuk P
Abstract excerpt
An Escherichia coli mutant pleiotropically altered in membrane-bound oxidoreductase activities was isolated following nitrosoguanidine treatment. Mutant R23 was able to grow on glucose, but was unable to grow on succinate or other oxidizable substrates as a sole energy source. Isolated membranes prepared from R23 failed to oxidize succinate and formate; while NADH was oxidized at a reduced rate by membranes. The...
Topics
- Chromosome Mapping
- Cytochromes
- Escherichia coli
- Formate Dehydrogenases
- L-Lactate Dehydrogenase
- Membrane Proteins
- Methylphenazonium Methosulfate
- Mutation
- NAD
- Nitrosoguanidines
- Oxidoreductases