Article
Mutation of the ptsG gene results in increased production of succinate in fermentation of glucose by Escherichia coli.
Applied and environmental microbiology - 1 Jan 2001
Chatterjee R, Millard C S, Champion K, Clark D P, Donnelly M I
Abstract excerpt
Escherichia coli NZN111 is blocked in the ability to grow fermentatively on glucose but gave rise spontaneously to a mutant that had this ability. The mutant carries out a balanced fermentation of glucose to give approximately 1 mol of succinate, 0. 5 mol of acetate, and 0.5 mol of ethanol per mol of glucose. The causative mutation was mapped to the ptsG gene, which encodes the membrane-bound, glucose-specific...
Topics
- Alleles
- Chromosome Mapping
- Culture Media
- Escherichia coli
- Fermentation
- Glucose
- Mutation
- Phosphoenolpyruvate Sugar Phosphotransferase System
- Succinic Acid