Article
Alterations of cellular physiology in Escherichia coli in response to oxidative phosphorylation impaired by defective F1-ATPase.
Journal of bacteriology - 1 Oct 2006
Noda Sakiko, Takezawa Yuji, Mizutani Tomohiko, Asakura Tomoaki, Nishiumi Eiichiro, Onoe Kazunori, Wada Masaru, Tomita Fusao, Matsushita Kazunobu, Yokota Atsushi
Abstract excerpt
The physiological changes in an F1-ATPase-defective mutant of Escherichia coli W1485 growing in a glucose-limited chemostat included a decreased growth yield (60%) and increased specific rates of both glucose consumption (168%) and respiration (171%). Flux analysis revealed that the mutant showed approximately twice as much flow in glycolysis but only an 18% increase in the tricarboxylic acid (TCA) cycle, owing...
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