Characterization of the complex pdxH-tyrS operon of Escherichia coli K-12 and pleiotropic phenotypes caused by pdxH insertion mutations.

doi:10.1128/jb.174.19.6033-6045.1992

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Article

Characterization of the complex pdxH-tyrS operon of Escherichia coli K-12 and pleiotropic phenotypes caused by pdxH insertion mutations.

Journal of bacteriology - 1 Oct 1992

Lam H M, Winkler M E

Abstract excerpt

We report the first molecular genetic analysis of a pyridoxine 5'-phosphate oxidase, the PdxH gene product of Escherichia coli K-12. Chromosomal insertions in and around pdxH were generated with various transposons, and the resulting phenotypes were characterized. The DNA sequence of pdxH was det...

Topics

Amino Acid Sequence
Base Sequence
Cell Division
Cloning, Molecular
Escherichia coli
Gene Expression Regulation, Bacterial
Genes, Bacterial
Glutamates
Glutamic Acid
Molecular Sequence Data
Mutagenesis, Insertional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Operon

Phenotype

Promoter Regions, Genetic

Pyridoxal Phosphate

Pyridoxaminephosphate Oxidase

RNA, Messenger

Sequence Homology

Source

Open in PubMed Open full text

Identifiers

PMID: 1356963
DOI: 10.1128/jb.174.19.6033-6045.1992
PMCID: PMC207668

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1356963-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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