Article
Evaluation of genetic manipulation strategies on D-lactate production by Escherichia coli.
Current microbiology - 1 Mar 2011
Zhou Li, Zuo Zhi-Rui, Chen Xian-Zhong, Niu Dan-Dan, Tian Kang-Ming, Prior Bernard A, Shen Wei, Shi Gui-Yang, Singh Suren, Wang Zheng-Xiang
Abstract excerpt
In order to rationally manipulate the cellular metabolism of Escherichia coli for D: -lactate production, single-gene and multiple-gene deletions with mutations in acetate kinase (ackA), phosphotransacetylase (pta), phosphoenolpyruvate synthase (pps), pyruvate formate lyase (pflB), FAD-binding D-lactate dehydrogenase (dld), pyruvate oxidase (poxB), alcohol dehydrogenase (adhE), and fumarate reductase (frdA) were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
