Article
Evolution of an Escherichia coli protein with increased resistance to oxidative stress.
The Journal of biological chemistry - 3 Apr 1998
Lu Z, Cabiscol E, Obradors N, Tamarit J, Ros J, Aguilar J, Lin E C
Abstract excerpt
L-1,2-Propanediol:NAD+ 1-oxidoreductase of Escherichia coli is encoded by the fucO gene, a member of the regulon specifying dissimilation of L-fucose. The enzyme normally functions during fermentative growth to regenerate NAD from NADH by reducing the metabolic intermediate L-lactaldehyde to propanediol which is excreted. During aerobic growth L-lactaldehyde is converted to L-lactate and thence to the central...
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