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Article

Beneficial effects of long-term treatment with SK&F 105685 in murine lupus nephritis.

The Journal of pharmacology and experimental therapeutics - 1 Oct 1990

Albrightson-Winslow C R, Brickson B, King A, Olivera D, Short B, Saunders C, Badger A M

Abstract excerpt

MRL/Mp-lpr/lpr (MRL/lpr) mice were studied from 6 to 19 weeks of age. Proteinuria began to increase at 15 weeks, and continued to increase until the animals were sacrificed at 19 weeks. This proteinuria was associated with lymphadenopathy and splenomegaly, as well as changes in lymph node cell phenotype and histologic changes in the glomeruli. Oral administration of SK&F 105685 starting at 12 weeks of age...

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Source

Identifiers

PMID: 2145424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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