Article
Late dominance of the inflammatory process in murine influenza by gamma/delta + T cells.
The Journal of experimental medicine - 1 Oct 1990
Carding S R, Allan W, Kyes S, Hayday A, Bottomly K, Doherty P C
Abstract excerpt
The inflammatory response in the lungs of mice infected with an influenza A virus consists largely of macrophages and CD3+ T cells. Most T lymphocytes recovered before day 7 after infection express mRNA for the T cell receptor alpha/beta (TCR-alpha/beta), while TCR-gamma/delta mRNA+ cells are found at much higher frequency over the next 7 d. The predominant surface phenotype for the TCR-gamma/delta mRNA+...
Topics
- Animals
- Female
- Heat-Shock Proteins
- Influenza A virus
- Mice
- Mice, Inbred C57BL
- Orthomyxoviridae Infections
- Phenotype
- Pneumonia
- RNA, Messenger
- Receptors, Antigen, T-Cell