Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a novel antigen-presenting cell population modulating antiinfluenza type 2 immunity.

The Journal of experimental medicine - 5 Jul 2010

Yoo Jae-Kwang, Galligan Carole L, Virtanen Carl, Fish Eleanor N

Abstract excerpt

Antiinfluenza type 2 (T2) immunity contributes to both immunopathology and immunoprotection, yet the underlying mechanisms modulating T2 immunity remain ill defined. We describe a novel mouse antigen (Ag)-presenting cell (APC), designated late-activator APC (LAPC). After pulmonary influenza A (H1N1) virus infection, LAPCs enter the lungs, capture viral Ag, and subsequently migrate to the draining lymph node (DLN)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen-Presenting Cells
Share to Antigens, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Polarity

Share to Immunity

Share to Influenza A Virus, H1N1 Subtype

Share to Lymph Nodes

Share to Orthomyxoviridae Infections

Share to Th2 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 20547825
DOI: 10.1084/jem.20091373
PMCID: PMC2901068

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a novel antigen-presenting cell population modulating antiinfluenza type 2 immunity.PMID 20547825Read ↗

Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors.Semantic proximity Read ↗

Inflammatory conditions shape phenotypic and functional characteristics of lung-resident memory T cells in miceSemantic proximity Read ↗

Nr4a1 marks a distinctive ILC2 activation subset in the mouse inflammatory lungSemantic proximity Read ↗

Progenitor T cells drive chronic pulmonary type 2 inflammationSemantic proximity Read ↗

Original encounter with antigen determines antigen-presenting cell imprinting of the quality of the immune response in mice.Semantic proximity Read ↗

Divergent effects of a Treg-selective IL-2 mutein on Influenza specific T cell responsesSemantic proximity Read ↗

In situ imaging reveals different responses by naïve and memory CD8 T cells to late antigen presentation by lymph node DC after influenza virus infection.Semantic proximity Read ↗

Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs.Semantic proximity Read ↗

Secondary CD8+ T-cell responses are controlled by systemic inflammation.Semantic proximity Read ↗

Allergic airways disease develops after an increase in allergen capture and processing in the airway mucosa.Semantic proximity Read ↗

Rapid reactivation of extralymphoid CD4 T cells during secondary infection.Semantic proximity Read ↗

DC subset–specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.