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Article

Sympathetic nervous system control of anti-influenza CD8 <sup>+</sup> T cell responses

13 Mar 2009

Abstract excerpt

Despite the longstanding appreciation of communication between the nervous and the immune systems, the nature and significance of these interactions to immunity remain enigmatic. Here, we show that 6-hydroxydopamine-mediated ablation of the mouse peripheral sympathetic nervous system increases primary CD8(+) T cell responses to viral and cellular antigens presented by direct priming or cross-priming. The...

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PMID: 19286971
DOI: 10.1073/pnas.0808851106

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