[Clinical relevance of drug metabolism polymorphisms].

doi:10.1024/0040-5930.57.9.573

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Article

[Clinical relevance of drug metabolism polymorphisms].

Therapeutische Umschau. Revue therapeutique - 1 Sept 2000

Mikus G

Abstract excerpt

Individual variation in drug response is a substantial clinical problem. Research in pharmacogenetics is currently evolving in two directions, firstly to identify genes and gene products associated with certain diseases, which may serve as targets for new drugs, and secondly to identify genes and allelic variants of genes that affect the expected and adverse response to current and future drugs. In that respect...

Topics

Algorithms
Arylamine N-Acetyltransferase
Cytochrome P-450 Enzyme System
Drug Resistance
Enzymes
Humans
Pharmacogenetics
Pharmacokinetics
Phenotype
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 11036438
DOI: 10.1024/0040-5930.57.9.573

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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