Article
[Therapeutic failure: importance of genes?].
Annales pharmaceutiques francaises - 1 Nov 2006
Lhermitte M, Allorge D, Broly F
Abstract excerpt
Drug management can be a difficult task in certain situations because of the variable response observed from one patient to another. Genetic factors affecting the pharmacokinetics and pharmacodynamics of drug reactions could explain the interindividual variability in drug response. Pharmacogenetic analysis provides insight into the molecular mechanisms involved in drug response, with the ultimate goal of...
Topics
- Animals
- Genetics
- Genotype
- Humans
- Metabolism
- Pharmacogenetics
- Phenotype
- Polymorphism, Genetic
- Treatment Failure
