Article
Genotypic characterization of two bacterial artificial chromosome clones derived from a single DNA source of the very virulent gallid herpesvirus-2 strain C12/130.
The Journal of general virology - 1 Jul 2011
Spatz Stephen J, Smith Lorraine P, Baigent Susan J, Petherbridge Lawrence, Nair Venugopal
Abstract excerpt
The identification of specific genetic changes associated with differences in the pathogenicity of Marek's disease virus strains (GaHV-2) has been a formidable task due to the large number of mutations in mixed-genotype populations within DNA preparations. Very virulent UK isolate C12/130 induces extensive lymphoid atrophy, neurological manifestations and early mortality in young birds. We have recently reported...
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