Article
Clustering of mutations within the inverted repeat regions of a serially passaged attenuated gallid herpesvirus type 2 strain.
Virus genes - 1 Aug 2008
Spatz Stephen J, Rue Cary, Schumacher Daniel, Osterrieder Nikolaus
Abstract excerpt
Marek's disease (MD) is the leading cause of losses in chicken production in the world. Over the past 40 years significant progress has been made in the control of MD through the use of vaccines which reduce or delay tumor formation in vaccinated flocks. However, these vaccines fail to induce an immune response that protects against infection and virus shedding. Little is known about the genetic changes that lead...
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