Article
A deletion in the glycoprotein L (gL) gene of U.S. Marek's disease virus (MDV) field strains is insufficient to confer increased pathogenicity to the bacterial artificial chromosome (BAC)-based strain, RB-1B.
Avian diseases - 1 Jun 2013
Shaikh Shireen A R, Katneni Upendra K, Dong Huimin, Gaddamanugu Syamsundar, Tavlarides-Hontz Phaedra, Jarosinski Keith W, Osterrieder Nikolaus, Parcells Mark S
Abstract excerpt
Marek's disease (MD) is a highly transmissible, herpesvirus-associated malignancy of chickens and turkeys caused by Marek's disease virus (MDV). MD is currently controlled through the use of nonsterilizing vaccines composed of antigenically related, apathogenic herpesviruses Mardivirus 2 (MDV-2), Meleagrid herpesvirus 1 (herpesvirus of turkeys, HVT), or attenuated MDV-1 strain CVI988 (Rispens). Since the...
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